Comparison of some permeability properties of rat-liver slices, liver cell in suspension, and in vivo-produced aggregates of dispersed liver cells

G KRANTI KUMAR & P M BHARGAVA

Regional Research Laboratory, Hyderabad-9, India

Published in: Journal of Membrane Biology, 1975, 22, 329-340.

Abstract:

It has been reported earlier that when rat liver is dispersed to a single cell suspension, the parenchymal cells lose the ability to take up pyrimidine bases but acquire the ability to take up RNAase and macromolecular nucleic acids. It is now shown that these changes are largely reversed on intraperitoneal reaggregation of the parenchymal cells and that, in these respects, the aggregates behave more like the organized tissue than like the dispersed cells.

PMID: 1159781

Keywords:
Biological Transport, Active, Cell Aggregation, DNA, Bacterial/metabolism, In Vitro Techniques, Liver/cytology, Liver/metabolism, Nucleic Acids/metabolism, Orotic Acid/metabolism, Permeability, RNA, Bacterial/metabolism, Ribonucleases/metabolism, Uracil/metabolism, Uridine/metabolism

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Comparison of some permeability properties of rat-liver slices, liver cell in suspension, and in vivo-produced aggregates of dispersed liver cells. G KRANTI KUMAR & P M BHARGAVA. Journal of Membrane Biology, 1975, 22, 329-340.

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