Effect of smeinalplasmin, an antimicrobial protein from bovine semen, on growth and macromolecular synthesis in Candida albicans

K H SCHEIT & P M BHARGAVA

Published in: Indian Journal of Biochemistry & Biophysics, 1985, 22, 1-7.

Abstract:

Seminalplasmin, an antimicrobial protein of bovine seminal plasma, inhibits growth and RNA, protein and DNA synthesis-in two strains of C. albicans in a yeast extract-glucose medium. The inhibition of protein and DNA syntheses is much less pronounced than of RNA synthesis which appears to be the primary target of seminalplasmin in this organism; in vitro, RNA synthesis but not protein synthesis is inhibited by seminalplasmin. RNA synthesis in protoplasts from C. albicans is significantly more sensitive to inhibition by seminalplasmin than RNA synthesis in the whole cells. It appears that seminalplasmin may act in C. albicans, as in E. coli, by penetrating the cells.

HOW TO CITE

Effect of smeinalplasmin, an antimicrobial protein from bovine semen, on growth and macromolecular synthesis in Candida albicans. K H SCHEIT & P M BHARGAVA. Indian Journal of Biochemistry & Biophysics, 1985, 22, 1-7.

READ THIS ARTICLE ONLINE OR ↓ DOWNLOAD A COPY

Download the full Paper from PMB memoir

➽ Full Text Online ↪ Download PDF

Having Trouble Downloading? ↪ Watch here how to download this article  ❙❙ ❚❚ ►

Tags: ,

Leave a Reply

Your email address will not be published. Required fields are marked *