A new synthesis of some derivatives of 4,4’ –stilbenediol

P. M. Bhargava  & S.H. Zaheer

Central Laboratories for Scientific and Industrial Research, Hyderabad, Deccan

Published in: Nature, 1953, 171, 746-747

Abstract:

Syntheses of α-alkyl- or α,α’-dialkyl-4,4′-stilbene- , diols and of their derivatives, several of which exhibit remarkable estrogenic activity, have so far mostly been by demethylation of the corresponding dimethyl ethers, and have invariably involved several stages.1,2 A direct synthesis in one step, of trans-α-methyl-4,4’stilbenediol (and some of its dialkyl ethers) from phenol (or its corresponding ether) and chloroacetone, has now been accomplished.

PMID: 13054700 | DOI: 10.1038/171746b0

Keywords:
Stilbenes

HOW TO CITE

A new synthesis of some derivatives of 4,4’ –stilbenediol. P M Bhargava & S H ZAHEER. Nature, 1953, 171, 746-747.

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