Seminalplasmin inhibits transcription and translation of DNA in vitro

VEENA N RAO1, E S P REDDY1, ANNAMARIA TORRIANI2 & P M BHARGAVA1

1Centre for Cellular and Molecular Biology, Hyderabad, India

Published in: FEBS Letters, 1983, 152, 6-10.

Abstract:

Seminalplasmin, an antimicrobial protein from bovine seminal plasma that has been earlier shown to inhibit transcription in whole cells and by purified RNA polymerase in vitro, but not translation in whole cells, is now shown to inhibit both transcription and translation independently of each other, in a coupled transcription-translation system from E. coli using phi80dphoAlacZ DNA as the template.

PMID: 6840278

Keywords:
Anti-Infective Agents/pharmacology, Cell-Free System, Coliphages, DNA, Viral/genetics, Gene Expression Regulation, Protein Biosynthesis/drug effects, Proteins/pharmacology, Semen/microbiology, Seminal Vesicle Secretory Proteins, Transcription, Genetic/drug effects

HOW TO CITE

Seminalplasmin inhibits transcription and translation of DNA in vitro. VEENA N RAO, E S P REDDY, ANNAMARIA TORRIANI & P M BHARGAVA, FEBS Letters, 1983, 152, 6-10.

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