Variation with age in dry weight and volume of liver parenchymal cells in the rate

L F HUSSAIN, B GOPINATH & P M BHARGAVA

Published in: Indian Journal of Experimental Biology, 1972, 10, 172-176.

Abstract:

Dry weight, volume, and dry weight per unit volume, of over 1300 parenchymal cells derived from livers of 3, 6, 9, 12 and 24 months old rats have been determined. The livers of older animals seemed to have a larger proportion of parenchymal cells with higher dry weight, larger volume, and lower dry weight per unit volume, in comparison to younger animals. Higher dry weight values were associated with larger volume for liver parenchymal cells of all the age groups studied ; cells with higher dry weights or larger volumes had, however, a lower value of dry weight per unit volume than cells with lower dry weight or smaller volume, except in the case of 3 months old animals. It is suggested that decrease in the number of parenchymal cells per unit wet weight of liver and in the concentration of cellular constituents, with age, may be partly responsible for the lower metabolic activity of the tissues of older animals.

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Variation with age in dry weight and volume of liver parenchymal cells in the rate. L F HUSSAIN, B GOPINATH & P M BHARGAVA. Indian Journal of Experimental Biology, 1972, 10, 172-176.

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