In vivo tissue-specific recognition by hepatic cells

K BHARGAVA & P M BHARGAVA

Regional Research Laboratory, Hyderabad-9, India

Published in: Experimental Cell Research, 1968, 50, 515-523

Abstract:

On intravenous injection of radioactive hepatic cells (obtained in suspension from the liver of a rat injected 24 h earlier with 32P-phosphate) into another rat, it is observed that 34–74 per cent (mean 49 per cent) of the injected radioactivity is recovered in the liver of the recipient animal. These and autoradiographic studies indicate that the injected hepatic cells can recognize their own kind in vivo and are incorporated as whole cells in the liver of the recipient animal. There is no localization of radioactivity in rabbit liver on injection of 32P-labelled rat hepatic cells.

PMID: 5663064

Keywords:
Autoradiography, Cell Aggregation, Injections, Intravenous, Liver/metabolism, Organ Size, Phosphates/metabolism, Phosphorus Isotopes

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In vivo tissue-specific recognition by hepatic cells. K BHARGAVA & P M BHARGAVA. Experimental Cell Research, 1968, 50, 515-523.

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